Search on: NEUROMUSCULAR BLOCKING AGENTS 
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Descriptor English:   Neuromuscular Blocking Agents 
Descriptor Spanish:   Agentes Bloqueadores Neuromusculares 
Descriptor Portuguese:   Bloqueadores Neuromusculares 
Tree Number:   D27.505.696.663.700.710
Definition English:   Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc. 
Indexing Annotation English:   GEN or unspecified; prefer specifics; consider also NEUROMUSCULAR JUNCTION /drug eff
History Note English:   75; was see under CURARE-LIKE AGENTS & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use urine
Record Number:   9658 
Unique Identifier:   D009466 

Occurrence in VHL:
 

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